4-(4-甲氧基苯基)丁烷-2-醇合成路线 （共 18 条）
反应条件
(-)-1-<4-methoxy-phenyl>-butanol-(3);
参考文献
Lederer; Polonsky
Trav. Soc. Chim. biol., 1942 , vol. 24, p. 1386,1390
反应条件
(-)-1-<4-methoxy-phenyl>-butanol-(3);
参考文献
Kin
Yakugaku Zasshi, 1942 , vol. 62, p. 455; 456; dtsch. Ref. S. 132, 133
Chem.Abstr., 1951 , p. 4222
反应条件
1: base 3: collidinium trifulorosulfonate / toluene / Heating View Scheme
参考文献
Denmark, Scott E.; Cresswell, Alexander J.
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12593 - 12628
反应条件
tris-buffer; nicotinamide adenine dinucleotide phosphate; acetone; Thermoanaerobacter ethanolicus (W110A TESADH) in water T=50°C; pH=8.0; 10 h;
参考文献
Musa, Musa M.; Ziegelmann-Fjeld, Karla I.; Vieille, Claire; Phillips, Robert S.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 5 p. 887 - 892
反应条件
α,α-diphenyl-5-methoxysalicyl alcohol; sulfuric acid in dichloromethane T=70°C; 10.3 h;
参考文献
Yang, Haishen; Mu, Feng; Wang, Pengfei
Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 8955 - 8961
反应条件
wet cells of Candida parapsilosis ATCC 7330 in aq. phosphate buffer; acetone T=25°C; pH=6.5; 11 h; Microbiological reaction; enantioselective reaction;
参考文献
RSC Advances, , vol. 4, # 5 p. 2257 - 2262
反应条件
sodium tetrahydroborate in methanol
T=0 - 20°C; 1 h; Inert atmosphere;
参考文献
Denmark, Scott E.; Cresswell, Alexander J.
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12593 - 12628
反应条件
tri-isobutyl aluminium in toluene
T=20°C; Rearrangement; 2 h;
参考文献
Du Roizel; Sollogoub; Pearce; Sinay
Chemical Communications, 2000 , # 16 p. 1507 - 1508
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in toluene
参考文献
Eli Lilly and Company
Patent: US5135955 A1, 1992 ;
反应条件
1: With tetrahydropyrrolo[2,1-c][1,2,4]triazole carbene; (Ph)2SiH2 in N,N-dimethyl-formamide; mineral oil
T=20°C; 6 h; Inert atmosphere;
2: With tetrabutyl ammonium fluoride in tetrahydrofuran; N,N-dimethyl-formamide; mineral oil
T=20°C; 0.5 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhao, Qiwu; Curran, Dennis P.; Malacria, Max; Fensterbank, Louis; Goddard, Jean-Philippe; Lacote, Emmanuel
Chemistry - A European Journal, 2011 , vol. 17, # 36 p. 9911 - 9914
