反应条件
1: 4-chloro-2-fluoro-1-iodobenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h; Inert atmosphere;
2: ethyl-α,α,α-trifluoroacetate in tetrahydrofuran; hexane
T=20°C;
参考文献
Connolly, Peter J.; Macielag, Mark J.; McDonnell, Mark E.; Zhu, Bin
Patent: US2012/77797 A1, 2012 ;
Location in patent: Page/Page column 31; 32 ;
US 20120077797 A1
