1,1'-(1,2-乙炔二基)二[4-碘-苯]合成路线 （共 17 条）
反应条件
1: With sulfuric acid; sodium nitrite in water
T=4 - 6°C; 0.75 h;
2: With potassium iodide in water
2 h;
参考文献
Fox, Mark A.; Howard, Judith A.K.; Hugh MacBride; Mackinnon, Angus; Wade, Kenneth
Journal of Organometallic Chemistry, 2003 , vol. 680, # 1-2 p. 155 - 164
反应条件
1.1: 55 percent / piperidine / (PPh3)2PdCl2; CuI / diethylamine / 40 h
2.1: NaNO2; H2SO4 / H2O / 0.75 h / 4 - 6 °C
2.2: 95 percent / KI / H2O / 2 h
View Scheme
参考文献
Fox, Mark A.; Howard, Judith A.K.; Hugh MacBride; Mackinnon, Angus; Wade, Kenneth
Journal of Organometallic Chemistry, 2003 , vol. 680, # 1-2 p. 155 - 164
反应条件
1.1: t-BuOK / toluene
1.2: 85 percent / toluene
2.1: Br2 / CCl4
3.1: t-BuOK / 20 °C
View Scheme
参考文献
Gonzalo Rodriguez; Esquivias, Jorge; Lafuente, Antonio; Diaz, Cristina
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8120 - 8128
反应条件
1.1: t-BuOK / toluene
1.2: 85 percent / toluene
2.1: Br2 / CCl4
3.1: t-BuOK / 20 °C
View Scheme
参考文献
Gonzalo Rodriguez; Esquivias, Jorge; Lafuente, Antonio; Diaz, Cristina
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8120 - 8128
反应条件
1: Br2 / CCl4
2: t-BuOK / 20 °C
View Scheme
参考文献
Gonzalo Rodriguez; Esquivias, Jorge; Lafuente, Antonio; Diaz, Cristina
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8120 - 8128
反应条件
1: NBS; benzoyl peroxide / CCl4 / 12 h / Heating
2: dimethylformamide / 12 h / 80 °C
View Scheme
参考文献
Orita, Akihiro; Miyamoto, Kazuhiko; Nakashima, Mikio; Ye, Fangguo; Otera, Junzo
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 7 p. 767 - 776
反应条件
1: 96 percent / manganese oxide / pyridine / 20 h / 60 °C
View Scheme
参考文献
Orita, Akihiro; Miyamoto, Kazuhiko; Nakashima, Mikio; Ye, Fangguo; Otera, Junzo
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 7 p. 767 - 776
反应条件
Multistep reaction.;
参考文献
Orita, Akihiro; Miyamoto, Kazuhiko; Nakashima, Mikio; Ye, Fangguo; Otera, Junzo
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 7 p. 767 - 776
反应条件
1: 87 percent / NEt3, CuI, Pd(PPh3)4 / toluene / 3 h / 40 °C
2: 1.) isoamylnitrite, 2.) KI / 1.) CHCl3, AcOH, 0 deg C, 20 min, 2.) 0 deg C to room temperature; 40 deg C, 2 h
View Scheme
参考文献
Mongin, Olivier; Gossauer, Albert
Tetrahedron, 1997 , vol. 53, # 20 p. 6835 - 6846
反应条件
1: 74 percent / KOH / propan-2-ol / 2.5 h / Heating
2: 87 percent / NEt3, CuI, Pd(PPh3)4 / toluene / 3 h / 40 °C
3: 1.) isoamylnitrite, 2.) KI / 1.) CHCl3, AcOH, 0 deg C, 20 min, 2.) 0 deg C to room temperature; 40 deg C, 2 h
View Scheme
参考文献
Mongin, Olivier; Gossauer, Albert
Tetrahedron, 1997 , vol. 53, # 20 p. 6835 - 6846
