sodium hydroxide in methanol T=20°C; 18 h;

potassium hydroxide T=90°C; 20 h;

1: 63.2 percent / sodium hydride / dimethylformamide / 8 h / 70 °C 2: 87.6 percent / 5 percent aq. NaOH / methanol / 18 h / 20 °C View Scheme

1: 62.5 percent / iron; acetic acid / 6.5 h / 80 °C 2: 63.2 percent / sodium hydride / dimethylformamide / 8 h / 70 °C 3: 87.6 percent / 5 percent aq. NaOH / methanol / 18 h / 20 °C View Scheme

1: 56.7 percent / NaHCO3; acetic anhydride / 6 h / 100 °C 2: 62.5 percent / iron; acetic acid / 6.5 h / 80 °C 3: 63.2 percent / sodium hydride / dimethylformamide / 8 h / 70 °C 4: 87.6 percent / 5 percent aq. NaOH / methanol / 18 h / 20 °C View Scheme

1: 99 percent / sodium dithionite, aq. ammonia / H2O / 1 h / 90 °C 2: 0.0003 mol / 10-ethyl-3-methyl-1,5-dihydro-5-deazaflavin-5-one, aq. potassium hydroxide / 20 h / 90 °C View Scheme

potassium hydroxide; 10-ethyl-3-methyl-1,5-dihydro-5-deazaflavin-5-one T=90°C; 20 h;