1.1: Li / tetrahydrofuran / 26 h 1.2: CuI / tetrahydrofuran / 0.33 h / -20 °C 1.3: 169 mg / tetrahydrofuran / 1 h / -20 °C 2.1: Li / tetrahydrofuran 2.2: CuBr*Me2S / tetrahydrofuran / 0.5 h / -20 °C 2.3: 670 mg / tetrahydrofuran; diethyl ether / 1 h / -78 - 0 °C 3.1: 96 percent / aq. HCl / tetrahydrofuran / 12 h / 20 °C 4.1: 66 percent / NH2OH*HCl; pyridine / ethanol / Heating 5.1: 54 percent / pyridine / CH2Cl2 / 4 h 6.1: 90 percent / Me3SiOTf / CH2Cl2 / 4 h / 0 °C 7.1: 59 percent / DIBAl / hexane / 2.5 h / 20 °C 8.1: 98 percent / H2 / Pd/C / ethyl acetate / 20 °C 9.1: 67 percent / TiCl4 / CH2Cl2 / 1 h / -78 °C 10.1: 74 percent / Et3N / CH2Cl2 / 1 h / 0 °C 11.1: 67 percent / LiAlH4 / diethyl ether / Heating View Scheme