17Alpha-羟基黄体酮合成路线 （共 90 条）
反应条件
1: 92 percent / aq. HClO4 / ethyl acetate / 0.1 h 2: 88 percent / KHCO3 / methanol / 2 h / Ambient temperature View Scheme
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
反应条件
toluene-4-sulfonic acid 0.0833333 h; microwave irradiation;
参考文献
Marwah, Padma; Marwah, Ashok; Lardy, Henry A.
Tetrahedron, 2003 , vol. 59, # 13 p. 2273 - 2287
反应条件
sodium tetrahydroborate in methanol T=0 - 5°C; 1.5 h;
参考文献
Kovganko; Kashkan; Shkumatov
Chemistry of Natural Compounds, 2001 , vol. 37, # 1 p. 55 - 56
反应条件
reduced form (20β-NADH); NADP; 20β-hydroxysteroid dehydrogenase in dichloromethane; water T=37°C; 20β-hydroxysteroid dehydrogenase activity with various cofactors and pH-s;
参考文献
Romo et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 1528,1530
参考文献
Camerino,B. et al.
Gazzetta Chimica Italiana, 1962 , vol. 92, p. 693 - 708
反应条件
glucose-6-phosphate; sporadic adrenal pheochromocytomas; oxygen; NADP; glucose 6-phosphate dehydrogenase T=37°C; 1 h; <4-14C>-labeled; Product distribution;
参考文献
Steroids, , vol. 54, # 6 p. 647 - 660
反应条件
G6P; 21-hydroxylase from human fetal adrenals; glucose-6-phosphate-dehydrogenase; potassium chloride; tri-(hydroxymethyl)-methylamine; magnesium chloride interaction with cytochrome P-450 obtained from microsomes and mitochondria from human fetal adrenals in dependence on conc.; apparent spectral dissociation const.; inhibition by danazol; Equilibrium constant;
参考文献
Wong, Luet-Lok
ChemBioChem, 2011 , vol. 12, # 17 p. 2537 - 2539
反应条件
1: 92 percent / aq. HClO4 / ethyl acetate / 0.1 h 2: 89 percent / NaBH4 / ethanol / Ambient temperature; other reagent View Scheme
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
反应条件
Cephalosporium aphidicola in ethanol
168 h;
参考文献
Farooq, Afgan; Hanson, James R.; Iqbal, Zahida
Phytochemistry (Elsevier), 1994 , vol. 37, # 3 p. 723 - 726
反应条件
mit Hilfe von Rhizopus arrhizus;
参考文献
Meister et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 416
