2-羟基-5H-二苯并(b,f)氮杂卓-5-甲酰胺合成路线 （共 11 条）
反应条件
potassium fluoride in water; acetonitrile 2.5 h; Heating; Yield given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
反应条件
acetic acid T=70°C; 2 h;
参考文献
Tian, Maoqun; Abdelrahman, Aliaa; Weinhausen, Stephanie; Hinz, Sonja; Weyer, Stefanie; Dosa, Stefan; El-Tayeb, Ali; Mueller, Christa E.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1077 - 1088
反应条件
triethylamine in chloroform carboxamidation; 72 h;
参考文献
Ju; Uetrecht; Van Koppen, Chris J.
Journal of Pharmacology and Experimental Therapeutics, 1999 , vol. 288, # 1 p. 51 - 56
反应条件
1: 95 percent / aq. Na2S2O4 / CHCl3 2: triethylamine / CHCl3 / 36 h / Ambient temperature 3: triethylamine / CCl4 / 2 h 4: NH3 / ethanol / 2 h / Heating 5: KF / acetonitrile; H2O / 2.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
反应条件
1: triethylamine / CHCl3 / 36 h / Ambient temperature 2: triethylamine / CCl4 / 2 h 3: NH3 / ethanol / 2 h / Heating 4: KF / acetonitrile; H2O / 2.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
反应条件
1: triethylamine / CCl4 / 2 h 2: NH3 / ethanol / 2 h / Heating 3: KF / acetonitrile; H2O / 2.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
反应条件
1: Fremy’s salt; disodium hydrogenphosphate / water; acetone / pH 7.22 / |Cooling 2: sodium dithionite; water / chloroform 3: triethylamine / chloroform / 72 h / 20 °C 4: chloroform / 48 h / 20 °C 5: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C View Scheme
反应条件
1: triethylamine / CHCl3 2: triethylamine / CCl4 3: 1.) 1,3-dibromo-5,5-dimethylhydantoin; 2.) 1,5-diazabicyclo<4.3.0>non-5-ene / 1.) tetrachloromethane, reflux 4: NH3 / ethanol / 2 h / Heating 5: KF / acetonitrile; H2O / 2.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
反应条件
1: triethylamine / CCl4 2: 1.) 1,3-dibromo-5,5-dimethylhydantoin; 2.) 1,5-diazabicyclo<4.3.0>non-5-ene / 1.) tetrachloromethane, reflux 3: NH3 / ethanol / 2 h / Heating 4: KF / acetonitrile; H2O / 2.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
反应条件
1: NH3 / ethanol / 2 h / Heating 2: KF / acetonitrile; H2O / 2.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, # 1 p. 237 - 238
