2,6-二甲基-N-(2-甲基苯基)苯胺合成路线 （共 4 条）
反应条件
NHC-Pd(II)-Im; potassium tert-butylate in toluene
4 h; Inert atmosphereReflux;
参考文献
Zhu, Lei; Ye, Yue-Mei; Shao, Li-Xiong
Tetrahedron, 2012 , vol. 68, # 10 p. 2414 - 2420
反应条件
potassium tert-butylate in 1,4-dioxane
T=110°C; 3 h;
参考文献
Chung, Kin Ho; So, Chau Ming; Wong, Shun Man; Luk, Chi Him; Zhou, Zhongyuan; Lau, Chak Po; Kwong, Fuk Yee
Synlett, 2012 , vol. 23, # 8 p. 1181 - 1186
反应条件
1: 1-bromo-2-methyl benzene With [Pd(1,3-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazol-2-ylidene)(cinnamyl)Cl]; potassium 2-methyl-2-butoxide in neat (no solvent)
T=25°C; Buchwald-Hartwig Coupling; 0.0833333 h;
2: 2,6-dimethylbenzeneamine in neat (no solvent)
T=25°C; Buchwald-Hartwig Coupling; 0.0833333 h;
参考文献
Chartoire, Anthony; Boreux, Arnaud; Martin, Anthony R.; Nolan, Steven P.
RSC Advances, 2013 , vol. 3, # 12 p. 3840 - 3843
反应条件
[Pd(N,N′-bis(2,6-bis(diphenylmethyl)-4-methoxyphenyl)imidazol-2-ylidene)(acac)Cl]; potassium 2-methyl-2-butoxide in 1,4-dioxane
T=20°C; Buchwald-Hartwig Coupling; 22 h; GloveboxInert atmosphere;
参考文献
Meiries, Sebastien; Speck, Klaus; Cordes, David B.; Slawin, Alexandra M. Z.; Nolan, Steven P.
Organometallics, 2013 , vol. 32, # 1 p. 330 - 339
