681482-81-5合成路线

1083099-55-1

681482-81-5

参考文献

OTSUKA PHARMACEUTICAL CO., LTD.
Patent: WO2008/140090 A1, 2008 ;
Location in patent: Page/Page column 42-43 ;

637-88-71,4-环己二酮+

287952-67-44-[4-(三氟甲氧基)苯氧基]哌啶

681482-81-5

参考文献

OTSUKA PHARMACEUTICAL CO., LTD.
Patent: WO2005/92832 A1, 2005 ;
Location in patent: Page/Page column 48-49 ;

681482-80-4

681482-81-5

参考文献

Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860

866109-93-5

681482-81-5

参考文献

OTSUKA PHARMACEUTICAL CO., LTD.
Patent: WO2008/140090 A1, 2008 ;
Location in patent: Page/Page column 34-35; 36-37 ;

36603-49-32-对溴苯氧基四氢吡喃

681482-81-5

参考文献

Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860

287952-67-44-[4-(三氟甲氧基)苯氧基]哌啶

681482-81-5

参考文献

Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860