trichlorophosphate in acetonitrile T=20°C; 7 h; Reflux;

1.1: trichlorophosphate / acetonitrile / 7 h / 20 °C / |Reflux 2.1: hydrogenchloride / dichloromethane; diethyl ether / 1 h / 5 - 20 °C 2.2: 5 h / |Reflux 3.1: palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; caesium carbonate / toluene / 1.5 h / 120 °C / |Inert atmosphere; |Microwave irradiation 4.1: bis-triphenylphosphine-palladium(II) chloride; sodium acetate / N,N-dimethyl acetamide / 1 h / 150 °C / |Inert atmosphere; |Microwave irradiation View Scheme