1: cis,cis-9,12-octadecadienoic acid With COMU®; N-ethyl-N,N-diisopropylamine in dichloromethane; acetonitrile T=20°C; 0.166667 h; Inert atmosphere; 2: ethanolamine in dichloromethane; acetonitrile T=20°C; Inert atmosphere;

pyridine

1: oxalyl chloride / dimethylformamide; benzene / 1 h / 0 °C 2: tetrahydrofuran; dimethylformamide; benzene / 0.25 h View Scheme

in dichloromethane T=20°C; 3 h; Inert atmosphere;