1-叔丁氧羰基氨基-2-乙烯基环丙烷甲酸乙酯合成路线 (共 5 条)
反应条件
1: T=20°C; Heating / reflux; 2: With hydrogenchloride in water T=20°C; 2 h;
参考文献
US2008/14173 A1, ;
Page/Page column 21 ;
US 20080014173 A1
反应条件
in tert-butyl methyl ether T=20°C; 100 h; Heating / reflux;
参考文献
US2006/183694 A1, ;
Page/Page column 35-36 ;
US 20060183694 A1
反应条件
sodium hydroxide; Alcalase in water; dimethyl sulfoxide T=39 - 40°C; pH=8; 67.1667 h; Sodium phosphate buffer; Product distribution / selectivity;
参考文献
US2008/14173 A1, ;
Page/Page column 22-23 ;
US 20080014173 A1
反应条件
Savinase in dimethyl sulfoxide T=40°C; pH=8.5; 18 h; Heps. Na buffer; Product distribution / selectivity;
参考文献
US2008/14173 A1, ;
Page/Page column 22-23 ;
US 20080014173 A1
反应条件
hydrogenchloride in 1,4-dioxane
T=20°C; 2 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2008/14173 A1, 2008 ;
Location in patent: Page/Page column 21 ;
US 20080014173 A1