5-乙氧基-2-恶唑羧酸乙酯合成路线 （共 5 条）
反应条件
phosphorus pentoxide in acetonitrile T=65 - 70°C; 1 h;
参考文献
Krapcho; Maresch; Gallagher; Hacker; Menta; Oliva; Di Domenico; Da Re; Spinelli
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1693 - 1702
反应条件
(i) Et3N, EtOH, (ii) POCl3, Et3N; Multistep reaction;
参考文献
Heterocycles, , vol. 9, p. 1271 - 1275
反应条件
1: aq. NaOH 2: 0.5 h / 100 °C View Scheme
参考文献
Kozikowski,A.P.; Isobe,K.
Heterocycles, 1978 , vol. 9, p. 1271 - 1275
反应条件
sodium hydroxide in water
1 h; Ambient temperature;
参考文献
Krapcho; Maresch; Gallagher; Hacker; Menta; Oliva; Di Domenico; Da Re; Spinelli
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1693 - 1702
反应条件
sodium tetrahydroborate; lithium chloride in ethanol
参考文献
AVEXA LIMITED
Patent: WO2007/124546 A1, 2007 ;
Location in patent: Page/Page column 63 ;
