6-氯-5-(环戊基甲基)-2,3-二氢-1H-茚-1-羧酸合成路线 （共 5 条）
反应条件
hydrogen; platinum(IV) oxide in ethanol
0.666667 h;
参考文献
Boettcher, Irmgard; Elger, Walter; Kirsch, Gerald; Siegmund, Fred; Wachtel, Helmut
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 413 - 414
反应条件
sodium hydroxide; hydrazine hydrate in water
参考文献
Schering Aktiengesellschaft
Patent: US4407823 A1, 1983 ;
反应条件
1: 62 percent / AlCl3 / CH2Cl2 / 0.75 h / -30 °C
2: 1.) NaH, DMSO / 1.) RT, 2.) RT, 30 min
3: 81 percent / H2 / PtO2 / ethanol / 0.67 h
View Scheme
参考文献
Boettcher, Irmgard; Elger, Walter; Kirsch, Gerald; Siegmund, Fred; Wachtel, Helmut
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 413 - 414
反应条件
1: 1.) NaH, DMSO / 1.) RT, 2.) RT, 30 min
2: 81 percent / H2 / PtO2 / ethanol / 0.67 h
View Scheme
参考文献
Boettcher, Irmgard; Elger, Walter; Kirsch, Gerald; Siegmund, Fred; Wachtel, Helmut
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 413 - 414
反应条件
1: 1.) NaH, DMSO / 1.) RT, 2.) RT, 30 min
2: 81 percent / H2 / PtO2 / ethanol / 0.67 h
View Scheme
参考文献
Boettcher, Irmgard; Elger, Walter; Kirsch, Gerald; Siegmund, Fred; Wachtel, Helmut
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 413 - 414
