2,2-二甲基-2,3-二氢-1-呋喃-7-胺合成路线 (共 6 条)
反应条件
hydrogen bromide; sodium nitrite; copper monobromide in water; Petroleum ether
参考文献
FMC Corporation
Patent: US5521190 A1, 1996 ;
反应条件
1: With trifluoroacetic acid in dichloromethane
T=20°C; 1.08333 h; Heating / reflux;
2: With sodium hydrogencarbonate in dichloromethane; water
参考文献
Clark, Jerry D.; Davis, Jamie M.; Favor, David; Fay, Lorraine K.; Franklin, Lloyd; Henegar, Kevin E.; Johnson, Douglas S.; Nichelson, Brian J.; Ou, Ligong; Repine, Joseph Thomas; Walters, Michael A.; White, Andrew David; Zhu, Zhijian
Patent: US2005/43309 A1, 2005 ;
Location in patent: Page/Page column 104 ;
反应条件
potassium hydroxide in dimethyl sulfoxide
T=140°C; 8 h; Green chemistry;
参考文献
Yu, Jianzhong; Zhang, Peizhi; Wu, Jun; Shang, Zhicai
Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3167 - 3170
反应条件
hydrogenchloride; sodium hydroxide; Magnesium chloride; sodium nitrite in water; acetic acid; toluene
参考文献
FMC Corporation
Patent: US4743291 A1, 1988 ;
反应条件
sulfuric acid; sulfur dioxide; sodium nitrite in water
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4514211 A1, 1985 ;
反应条件
hydrogenchloride; sulfuric acid; sulfur dioxide; acetic acid; sodium nitrite in water
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4589909 A1, 1986 ;