3-氯-4-氰基吡啶合成路线

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MERCK SHARP and DOHME CORP.; GILBERT, Eric, J.; CUMMING, Jared, N.; STAMFORD, Andrew, W.; YU, Younong; SCOTT, Jack, D.; ISERLOH, Ulrich; WANG, Lingyan; CALDWELL, John, P.
Patent: WO2014/62553 A1, 2014 ;
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68325-15-53-氯-4-氰基吡啶

654663-32-83-甲氧基-4-吡啶羧酸

参考文献

Yuan, Yunyun; Elbegdorj, Orgil; Chen, Jianyang; Akubathini, Shashidhar K.; Zhang, Feng; Stevens, David L.; Beletskaya, Irina O.; Scoggins, Krista L.; Zhang, Zhenxian; Gerk, Phillip M.; Selley, Dana E.; Akbarali, Hamid I.; Dewey, William L.; Zhang, Yan
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 10118 - 10129

68325-15-53-氯-4-氰基吡啶

114080-93-2异噁唑并[4,5-b]吡啶-3-胺

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Dunn, A. D.
Zeitschrift fuer Chemie (Stuttgart, Germany), 1987 , vol. 27, # 9 p. 337 - 338

68325-15-53-氯-4-氰基吡啶+

5188-07-8甲硫醇钠

13600-45-83-(甲基磺酰基)吡啶-4-甲腈

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SUMITOMO CHEMICAL COMPANY, LIMITED; OTSUKI, Junko
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68325-15-53-氯-4-氰基吡啶

118160-04-6

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Sakamoto, Takao; An-Naka, Masayuki; Kondo, Yoshinori; Araki, Tomio; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 5 p. 1890 - 1894

546-88-3乙酰氧肟酸+

68325-15-53-氯-4-氰基吡啶

114080-94-3异噁唑并[5,4-c]吡啶-3-胺

参考文献

Tichenor, Mark S.; Keith, John M.; Jones, William M.; Pierce, Joan M.; Merit, Jeff; Hawryluk, Natalie; Seierstad, Mark; Palmer, James A.; Webb, Michael; Karbarz, Mark J.; Wilson, Sandy J.; Wennerholm, Michelle L.; Woestenborghs, Filip; Beerens, Dominiek; Luo, Lin; Brown, Sean M.; Boeck, Marlies De; Chaplan, Sandra R.; Breitenbucher, J. Guy
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68325-15-53-氯-4-氰基吡啶

114080-94-3异噁唑并[5,4-c]吡啶-3-胺

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JANSSEN PHARMACEUTICA NV; BREITENBUCHER, J., Guy; KEITH, John, M.; TICHENOR, Mark, S.; CHAMBERS, Alison, L.; JONES, William, M.; HAWRYLUK, Natalie, A.; TIMMONS, Amy, K.; MERIT, Jeffrey, E.; SEIERSTAD, Mark, J.
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68325-15-53-氯-4-氰基吡啶+

2365-48-2巯基乙酸甲酯

111042-91-2甲基3-氨基噻吩并[2,3-c]吡啶-2-羧酸酯

参考文献

Dunn, A. D.; Norrie, R.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 85 - 89

1993-03-92-氟苯硼酸+

68325-15-53-氯-4-氰基吡啶

868944-77-8

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Cailly, Thomas; Fabis, Frederic; Rault, Sylvain
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75-16-1甲基溴化镁+

68325-15-53-氯-4-氰基吡啶

78790-82-61-(3-氯-4-吡啶)-乙酮

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LaMattina, John L.; Taylor, Richard L.
Journal of Organic Chemistry, 1981 , vol. 46, # 21 p. 4179 - 4182