(3aS,6aR)-2,2-二甲基-4,6a-二氢-3aH-环戊二烯并[d][1,3]二氧杂环戊烯-4-醇合成路线 （共 2 条）
反应条件
pyridinium chlorochromate in dichloromethane 24 h;
参考文献
Clive, Derrick L. J.; Liu, Dazhan
Journal of Organic Chemistry, 2008 , vol. 73, # 8 p. 3078 - 3087
反应条件
1: PCC / CH2Cl2
2: 80 percent / CuBr*Me2S; TMSCl; HMPA / tetrahydrofuran / -78 - 0 °C
3: 98 percent / LiAlH4 / tetrahydrofuran / 3 h / 20 °C
4: DIAD; Ph3P / tetrahydrofuran / 0 - 20 °C
5: NaIO4; OsO4 / methanol; H2O / 3 h / 0 - 20 °C
6: 2.09 g / NaBH4 / methanol / 1 h / 0 °C
7: 91 percent / NH3 / methanol / 24 h / 100 °C
8: 95 percent / aq. HCl / methanol / 3 h / 20 °C
View Scheme
参考文献
Yang, Minmin; Ye, Wei; Schneller, Stewart W.
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3993 - 3996
