1: DIBALH / CH2Cl2 / -78 °C 2: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C 3: 100 percent / DCC / CH2Cl2 / 20 °C 4: 76 percent / n-Bu3P / toluene / 20 °C 5: NaH / dimethylformamide / 0 - 20 °C 6: n-BuONO; KHMDS / tetrahydrofuran / 0 °C 7: Zn; TFA / CH2Cl2 / 20 °C View Scheme

1: DIBALH / CH2Cl2 / -78 °C 2: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C 3: 100 percent / DCC / CH2Cl2 / 20 °C 4: 76 percent / n-Bu3P / toluene / 20 °C View Scheme

1: DIBALH / CH2Cl2 / -78 °C 2: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C 3: 100 percent / DCC / CH2Cl2 / 20 °C 4: 76 percent / n-Bu3P / toluene / 20 °C 5: NaH / dimethylformamide / 0 - 20 °C View Scheme