(1-苯基-1H-吡唑并[3,4-d]嘧啶-4-基)-肼合成路线 （共 5 条）
反应条件
hydrazine hydrate in water; benzene
T=20°C; 1 h;
参考文献
Abd El Razik, Heba A.; Abdel Wahab, Abeer E.
Archiv der Pharmazie, 2011 , vol. 344, # 3 p. 184 - 196
反应条件
hydrazine hydrate in ethanol
T=45°C; 24 h;
参考文献
Peat, Andrew J.; Boucheron, Joyce A.; Dickerson, Scott H.; Garrido, Dulce; Mills, Wendy; Peckham, Jennifer; Preugschat, Frank; Smalley, Terrence; Schweiker, Stephanie L.; Wilson, Jayme R.; Wang, Tony Y.; Zhou, Huiqiang Q.; Thomson, Stephen A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2121 - 2125
反应条件
1: H2O / 24 h / Heating
2: POCl3; DMF / 4 h / Heating
3: hydrazine hydrate / ethanol / 24 h / 45 °C
View Scheme
参考文献
Peat, Andrew J.; Boucheron, Joyce A.; Dickerson, Scott H.; Garrido, Dulce; Mills, Wendy; Peckham, Jennifer; Preugschat, Frank; Smalley, Terrence; Schweiker, Stephanie L.; Wilson, Jayme R.; Wang, Tony Y.; Zhou, Huiqiang Q.; Thomson, Stephen A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2121 - 2125
反应条件
1: POCl3; DMF / 4 h / Heating
2: hydrazine hydrate / ethanol / 24 h / 45 °C
View Scheme
参考文献
Peat, Andrew J.; Boucheron, Joyce A.; Dickerson, Scott H.; Garrido, Dulce; Mills, Wendy; Peckham, Jennifer; Preugschat, Frank; Smalley, Terrence; Schweiker, Stephanie L.; Wilson, Jayme R.; Wang, Tony Y.; Zhou, Huiqiang Q.; Thomson, Stephen A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2121 - 2125
反应条件
1: ethanol / 4 h / Heating
2: H2O / 24 h / Heating
3: POCl3; DMF / 4 h / Heating
4: hydrazine hydrate / ethanol / 24 h / 45 °C
View Scheme
参考文献
Peat, Andrew J.; Boucheron, Joyce A.; Dickerson, Scott H.; Garrido, Dulce; Mills, Wendy; Peckham, Jennifer; Preugschat, Frank; Smalley, Terrence; Schweiker, Stephanie L.; Wilson, Jayme R.; Wang, Tony Y.; Zhou, Huiqiang Q.; Thomson, Stephen A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2121 - 2125
