(R)-1-(+)-2-哌啶乙醇合成路线 (共 11 条)
反应条件
1: With hydrogenchloride; sodium hypochlorite; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; potassium bromide in water; ethyl acetate
T=5 - 20°C; pH=8.0 - 9.0; 0.833333 h;
2: With hydrogenchloride; sodium chlorite in water; ethyl acetate
T=20 - 33°C; pH=5.0; 16.5 h;
参考文献
FUJISAWA PHARMACEUTICAL CO., LTD.
Patent: EP1426359 A1, 2004 ;
Location in patent: Page 5 ;