4-三甲基甲硅烷基甲基吡啶合成路线 （共 8 条）
反应条件
hydrogenchloride; potassium fluoride; 18-crown-6 or silica-supported tetrabutylammonium fluoride in tetrahydrofuran T=20°C; 12 h; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 23, # 5 p. 577 - 578
反应条件
hydrogenchloride; potassium fluoride; 18-crown-6 or silica-supported tetrabutylammonium fluoride in tetrahydrofuran T=20°C; 12 h; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 23, # 5 p. 577 - 578
反应条件
hydrogenchloride; potassium fluoride; 18-crown-6 or silica-supported tetrabutylammonium fluoride in tetrahydrofuran T=20°C; 12 h; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 23, # 5 p. 577 - 578
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; dichloromethane 20 h; Ambient temperature;
参考文献
Andrews, Ian P.; Lewis, Norman J.; McKillop, Alexander; Wells, Andrew S.
Heterocycles, 1996 , vol. 43, # 6 p. 1151 - 1158
反应条件
1: LDA / tetrahydrofuran / 0.5 h / 0 °C 2: 59 percent / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Anders; Opitz; Bauer
Synthesis, 1991 , # 12 p. 1221 - 1227
反应条件
1: 4-Methylpyridine With methyllithium in diethyl ether
0.5 h; Heating;
2: chloro-trimethyl-silane in diethyl ether
0.5 h;
参考文献
Happer, Alan; N.G, Janice; Pool, Brett; White, Jonathan
Journal of Organometallic Chemistry, 2002 , vol. 659, # 1-2 p. 10 - 14
反应条件
1: 4-Methylpyridine With methyllithium in diethyl ether
2: chloro-trimethyl-silane in diethyl ether
参考文献
Happer, Alan; N.G, Janice; Pool, Brett; White, Jonathan
Journal of Organometallic Chemistry, 2002 , vol. 659, # 1-2 p. 10 - 14
反应条件
hydrogenchloride; potassium fluoride; 18-crown-6 or silica-supported tetrabutylammonium fluoride in tetrahydrofuran
T=20°C; 12 h; Yields of byproduct given;
参考文献
Ricci, Alfredo; Degl'Innocenti, Alessandro; Fiorenza, Mariella; Taddei, Maurizio; Spartera, Maria A.; Walton, David R.M.
Tetrahedron Letters, 1982 , vol. 23, # 5 p. 577 - 578
