5-氨基-1-苄基-1H-咪唑-4-羧酸乙酯合成路线 （共 15 条）
参考文献
Mackenzie, Grahame; Wilson, Hilary A.; Shaw, Gordon; Ewing, David
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2541 - 2546
反应条件
in acetic acid 1 h; Heating;
参考文献
Mackenzie, Grahame; Wilson, Hilary A.; Shaw, Gordon; Ewing, David
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2541 - 2546
反应条件
1: 84 percent / hydrazine hydrate (85 percent) / ethanol / 312 h / Heating 2: 75 percent / trifluoroacetic acid / 2 h / 85 °C 3: 68 percent / sodium nitrite, acetic acid (glacial) / H2O / r.t., overnight View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, p. 753 - 755
反应条件
1.1: 100 percent / aq. NaOH / ethanol / 5 h / Heating
2.1: 76 percent / dimethylformamide / 2 h / 80 °C
3.1: NaOH / tetrahydrofuran; ethanol; H2O / 3 h / 26 °C
3.2: 68 percent / Ac2O; AcOH / 96 h / 130 °C
View Scheme
参考文献
Lin, Xiaoyu; Robins, Morris J.
Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 7 p. 1029 - 1041
反应条件
1: 100 percent / aq. NaOH / ethanol / 5 h / Heating
2: 76 percent / dimethylformamide / 2 h / 80 °C
3: N2H4*H2O / ethanol / 0.33 h / 20 °C
4: aq. HCl; NaNO2 / diethyl ether
5: 43.1 mg / TFA / toluene / 24 h / Heating
View Scheme
参考文献
Lin, Xiaoyu; Robins, Morris J.
Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 7 p. 1029 - 1041
