N-(苄氧基羰基)-1,2,3,4-四氢吡啶合成路线 （共 25 条）
反应条件
Oxonereg;; potassium carbonate in acetone T=20°C; 2 h;
参考文献
Takeuchi, Yasuo; Oshige, Miyo; Azuma, Kumiko; Abe, Hitoshi; Harayama, Takashi
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 7 p. 868 - 869
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane
T=-78 - 0°C; Swern oxidation;
2: With hydrogenchloride in dichloromethane
T=20°C; 15 h; Further stages.;
参考文献
Okitsu; Suzuki; Kobayashi
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 809 - 823
反应条件
trimethylsilylazide; iodosylbenzene in dichloromethane
T=-45 - -25°C;
参考文献
Magnus, Philip; Hulme, Christopher; Weber, Wolfgang
Journal of the American Chemical Society, 1994 , vol. 116, # 10 p. 4501 - 4502
反应条件
sodium tetrahydroborate; nickel dichloride in methanol; ethylene glycol dimethyl ether
T=20°C; 0.166667 h; regioselective reaction;
参考文献
Yin, Biao-Lin; Cai, Cong-Bi; Lai, Jin-Qiang; Zhang, Ze-Ren; Huang, Li; Xu, Li-Wen; Jiang, Huan-Feng
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 18 p. 3319 - 3324
反应条件
sulfuric acid in tetrahydrofuran
T=20°C; 1 h;
参考文献
Takeuchi, Yasuo; Azuma, Kumiko; Abe, Hitoshi; Sasaki, Kenji; Harayama, Takashi
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 7 p. 1011 - 1012
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triphenylphosphine in 1,4-dioxane
T=90°C; 5 h;
参考文献
Occhiato, Ernesto G.; Lo Galbo, Fabrizio; Guarna, Antonio
Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7324 - 7330
反应条件
bromobenzene; potassium carbonate; trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) in toluene
T=110°C; 4 h;
参考文献
Ferrali, Alessandro; Guarna, Antonio; Lo Galbo, Fabrizio; Occhiato, Ernesto G.
Tetrahedron Letters, 2004 , vol. 45, # 27 p. 5271 - 5274
反应条件
ammonium chloride
Heating;
参考文献
Moriyama, Noriaki; Matsumura, Yoshihiro; Kuriyama, Masami; Onomura, Osamu
Tetrahedron Asymmetry, 2009 , vol. 20, # 23 p. 2677 - 2687
反应条件
triethylamine in tetrahydrofuran
3 h; Reflux;
参考文献
de Almeida, Valderes Moraes; dos Santos, Rosiel Jose; da Silva Goes, Alexandre Jose; de Lima, Jose Gildo; Duarte Correia, Carlos Roque; de Faria, Antonio Rodolfo
Tetrahedron Letters, 2009 , vol. 50, # 6 p. 684 - 687
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in 1,4-dioxane
T=100°C; 1.5 h; Product distribution; Further Variations:ReagentsSolventsTemperatures;
参考文献
Ferrali, Alessandro; Guarna, Antonio; Lo Galbo, Fabrizio; Occhiato, Ernesto G.
Tetrahedron Letters, 2004 , vol. 45, # 27 p. 5271 - 5274
