1,2,3,4-四氢萘-1-乙醇合成路线 （共 16 条）
反应条件
1: 1) LDA / 1) THF, hexane, -78 deg C, 10 min, 2) a) -78 deg C, 2 h, b) -20 deg C, 2 h, c) to r.t., 2 h
2: 82 percent / H2 / Pd/C / ethanol / 4 h
3: 92 percent / LiAlH4 / diethyl ether / 2 h / 0 °C
View Scheme
参考文献
Novak, Lajos; Rohaly, Janos; Poppe, Laszlo; Hornyanszky, Gabor; Kolonits, Pal; et al.
Liebigs Annalen der Chemie, 1992 , # 2 p. 145 - 158
反应条件
1: 82 percent / H2 / Pd/C / ethanol / 4 h
2: 92 percent / LiAlH4 / diethyl ether / 2 h / 0 °C
View Scheme
参考文献
Novak, Lajos; Rohaly, Janos; Poppe, Laszlo; Hornyanszky, Gabor; Kolonits, Pal; et al.
Liebigs Annalen der Chemie, 1992 , # 2 p. 145 - 158
反应条件
diisobutylaluminium hydride in hexane; toluene
T=-78 - 20°C; 12 h;
参考文献
Takeda, Momotaro; Takatsu, Keishi; Shintani, Ryo; Hayashi, Tamio
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2354 - 2367
反应条件
tin(IV) chloride in dichloromethane
1.) reflux, 4 h, 2.) room temp., 19 h; Further byproducts given;
参考文献
Taylor, Stephen K.; Hockerman, Gregory H.; Karrick, Gregory L.; Lyle, Stephen B.; Schramm, Scott B.
Journal of Organic Chemistry, 1983 , vol. 48, # 15 p. 2449 - 2452
参考文献
v. Braun; Reutter
Chemische Berichte, 1926 , vol. 59, p. 1926
反应条件
1: benzene; p-toluenesulfonic acid
2: palladium/charcoal / 290 - 300 °C
View Scheme
参考文献
Newman; O'Leary
Journal of the American Chemical Society, 1946 , vol. 68, p. 258,259
