3-碘代-1-甲基-1H-吡唑并[3,4-b]吡啶合成路线 （共 2 条）
反应条件
1: With sulfuric acid; sodium nitrite in water
T=0°C; 1.5 h;
2: With potassium iodide in water
T=0 - 20°C; Further stages.;
参考文献
Lavecchia; Berteina-Raboin; Guillaumet
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2389 - 2392
反应条件
1.1: 93 percent / Cs2CO3; o-phenanthroline; CuI / dimethylformamide / 12 h / 60 °C
2.1: H2SO4; NaNO2 / H2O / 1.5 h / 0 °C
2.2: 70 percent / KI / H2O / 0 - 20 °C
View Scheme
参考文献
Lavecchia; Berteina-Raboin; Guillaumet
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2389 - 2392
