1: 3'-bromo-2'-hydroxychalcone With zinc(II) chloride in dichloromethane T=20°C; 12 h; 2: 3,4,5-trimethoxyphenylboronic acid With tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether Suzuki coupling; Inert atmosphereReflux; 3: With dihydrogen peroxide in tetrahydrofuran; water T=0°C; 1 h; regioselective reaction;