3-甲基-异恶唑并[5,4-d]嘧啶-4(5H)-酮合成路线 （共 5 条）
反应条件
sodium ethanolate in ethanol
7 h; Heating;
参考文献
Miyashita, Akira; Fujimoto, Katsuhiro; Okada, Tomomi; Higashino, Takeo
Heterocycles, 1996 , vol. 42, # 2 p. 691 - 699
反应条件
T=190°C; 4 h; Neat (no solvent)Inert atmosphere;
参考文献
Ho, Jonathan Z.; Van Arsdale, Kyle R.; Braun, Matthew P.
Helvetica Chimica Acta, 2008 , vol. 91, # 5 p. 958 - 963
反应条件
acetic anhydride
3 h; Heating;
参考文献
Taylor,E.C.; Garcia,E.E.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2116 - 2120
反应条件
1: (i) H2SO4, (ii) aq. NH3
2: Ac2O / 3 h / Heating
View Scheme
参考文献
Taylor,E.C.; Garcia,E.E.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2116 - 2120
反应条件
1: NH2OH*HCl, aq. NaOH
2: (i) H2SO4, (ii) aq. NH3
3: Ac2O / 3 h / Heating
View Scheme
参考文献
Taylor,E.C.; Garcia,E.E.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2116 - 2120
