N-苄基-N-甲基-4-哌啶甲酰胺合成路线 （共 4 条）
参考文献
Kolodziej, Stephen A.; Hockerman, Susan L.; Decrescenzo, Gary A.; McDonald, Joseph J.; Mischke, Debbie A.; Munie, Grace E.; Fletcher, Theresa R.; Stehle, Nathan; Swearingen, Craig; Becker, Daniel P.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 12 p. 3561 - 3564
反应条件
1: toluene / Ambient temperature
2: HBr / acetic acid / 4 h / 0 - 20 °C
View Scheme
参考文献
Alabaster, Valerie A.; Campbell, Simon F.; Danilewicz, John C.; Greengrass, Colin W.; Plews, Rhona M.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 999 - 1003
反应条件
1: toluene / Ambient temperature
2: HBr / acetic acid / 4 h / 0 - 20 °C
View Scheme
参考文献
Alabaster, Valerie A.; Campbell, Simon F.; Danilewicz, John C.; Greengrass, Colin W.; Plews, Rhona M.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 999 - 1003
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 18 h / 20 °C
2: hydrogenchloride / ethyl acetate; water / 2 h / 20 °C
View Scheme
参考文献
Hu, Suwen; Gu, Quan; Wang, Zhilong; Weng, Zhiyong; Cai, Yunrui; Dong, Xiaowu; Hu, Yongzhou; Liu, Tao; Xie, Xin
European Journal of Medicinal Chemistry, 2014 , vol. 71, p. 259 - 266
