4-氯-3,4-二甲基-2-吡唑啉-5-酮合成路线 （共 12 条）
反应条件
1: 12.5 percent / hydrated potassium carbonate / CH2Cl2 / 12 h / Ambient temperature 2: 49 percent / Br2 / CH2Cl2 / Ambient temperature View Scheme
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
反应条件
1: 12.5 percent / hydrated potassium carbonate / CH2Cl2 / 12 h / Ambient temperature 2: 2.2 percent / Br2 / CH2Cl2 / Ambient temperature View Scheme
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
反应条件
potassium carbonate in dichloromethane 1.) ice bath, 1 h, 2.) room temperature, 18 h;
参考文献
Journal of the American Chemical Society, , vol. 102, p. 4983
反应条件
potassium carbonate in dichloromethane 12 h; Ambient temperature;
参考文献
Journal of the American Chemical Society, , vol. 102, p. 4983
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane 1.) 0 deg C, 1 h, 2.) 24 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 47, # 2 p. 207 - 213
反应条件
potassium carbonate 72 h;
参考文献
Journal of the American Chemical Society, , vol. 102, p. 4983
反应条件
1: 12.5 percent / hydrated potassium carbonate / CH2Cl2 / 12 h / Ambient temperature 2: 45 percent / 10percent HCl / 15 h / Heating View Scheme
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
1.) 0 deg C, 1 h, 2.) 24 h; Further byproducts given;
参考文献
Kanety, Hannah; Dodiuk, Hanna; Kosower, Edward M.
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 207 - 213
反应条件
1: 52 percent / i-Pr2NEt / CH2Cl2 / Ambient temperature
2: 58 percent / Br2 / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
1.) ice bath, 1 h, 2.) 2 h; Further byproducts given;
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
