1: in methanol; water T=60°C; 0.5 h; 2: With sodium carbonate in water T=60°C; 1.5 h;

potassium carbonate in acetone

1.1: sodium hydroxide; hydrogen / methanol / 12 h / 100 °C / |Inert atmosphere 2.1: methanol / 6 h / |Reflux 2.2: 4 h / 60 - 90 °C 3.1: methanol; water / 0.5 h / 60 °C 3.2: 1.5 h / 60 °C View Scheme

1.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 - 90 °C / |Large scale 1.2: 4 h / 50 °C / |Large scale 2.1: sodium hydroxide; hydrogen / methanol / 12 h / 100 °C / |Inert atmosphere 3.1: methanol / 6 h / |Reflux 3.2: 4 h / 60 - 90 °C 4.1: methanol; water / 0.5 h / 60 °C 4.2: 1.5 h / 60 °C View Scheme

1.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 - 90 °C / |Large scale 1.2: 4 h / 50 °C / |Large scale 2.1: sodium hydroxide; hydrogen / methanol / 12 h / 100 °C / |Inert atmosphere 3.1: methanol / 6 h / |Reflux 3.2: 4 h / 60 - 90 °C 4.1: methanol; water / 0.5 h / 60 °C 4.2: 1.5 h / 60 °C View Scheme

1.1: methanol / 6 h / |Reflux 1.2: 4 h / 60 - 90 °C 2.1: methanol; water / 0.5 h / 60 °C 2.2: 1.5 h / 60 °C View Scheme

3-chloro-benzenecarboperoxoic acid in dichloromethane a) 10 deg C, 1 h, b) r.t., 12 h;