反应条件
1: 100 percent / 2.5 N NaOH, / tetrahydrofuran; H2O / 6 h
2: N-methylmorpholine / ethyl acetate / 0.2 h / -5 °C
3: N-methylmorpholine / ethyl acetate; dimethylformamide / 1.5 h / -5 °C
4: 2.5 N NaOH / tetrahydrofuran; H2O / 6 h
5: HCl(gas) / ethyl acetate / 0.75 h / 0 °C
6: 76.6 percent / diphenylphosphoryl azide (DPPA), NaHCO3 / dimethylformamide / 72 h / 0 - 5 °C
7: HCOOH / 10percent Pd/C / methanol / 2.5 h
View Scheme
参考文献
Brady; Freidinger; Paleveda; et al.
Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 764 - 769
