2-羟基甲基-2-环戊酮合成路线 （共 25 条）
反应条件
(dimethyl)(phenyl)phosphine in chloroform; water
T=20°C; Morita-Baylis-Hillman reaction; 1 h;
参考文献
Bonazzi, Simone; Binaghi, Massimo; Fellay, Cindy; Wach, Jean-Yves; Gademann, Karl
Synthesis, 2010 , # 4 art. no. T17809SS, p. 631 - 642
反应条件
diisobutylaluminium hydride in tetrahydrofuran; hexane
T=-78°C; 2 h;
参考文献
Smith, Amos B.; Dorsey, Bruce D.; Ohba, Masashi; Lupo, Andrew T.; Malamas, Michael S.
Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4314 - 4325
反应条件
4-methylmorpholine N-oxide in dichloromethane
T=20°C; Cycloaddition; Khand cycloaddition;
参考文献
Kerr, William J.; McLaughlin, Mark; Pauson, Peter L.; Robertson, Sarah M.
Chemical Communications, 1999 , # 21 p. 2171 - 2172
反应条件
N-methyl-pyrrolidine in water
T=20°C; 90 h;
参考文献
Guerra, Krassimira P.; Afonso, Carlos A. M.
European Journal of Organic Chemistry, 2011 , # 12 p. 2372 - 2379
反应条件
pyridinium p-toluenesulfonate in methanol
1 h; Heating;
参考文献
Kerr, William J.; McLaughlin, Mark; Pauson, Peter L.; Robertson, Sarah M.
Journal of Organometallic Chemistry, 2001 , vol. 630, # 1 p. 104 - 117
反应条件
1,4-diaza-bicyclo[2.2.2]octane; water in N,N-dimethyl-formamide
T=20°C; 8 h;
参考文献
Zhu, Bo; Yan, Lin; Pan, Yuanhang; Lee, Richmond; Liu, Hongjun; Han, Zhiqiang; Huang, Kuo-Wei; Tan, Choon-Hong; Jiang, Zhiyong
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6894 - 6900
反应条件
1: propargyl alcohol With dicobalt octacarbonyl
2: benzoic acid vinyl ester With 4-methylmorpholine N-oxide in dichloromethane
T=25°C; Khand cyclization; 18 h;
参考文献
Kerr, William J.; McLaughlin, Mark; Pauson, Peter L.; Robertson, Sarah M.
Journal of Organometallic Chemistry, 2001 , vol. 630, # 1 p. 104 - 117
参考文献
Itoh, Akira; Ozawa, Shuji; Oshima, Koichiro; Nozaki, Hitosi
Tetrahedron Letters, 1980 , vol. 21, p. 361 - 364
反应条件
Ba(OH)2 in methanol
T=20°C; 0.666667 h;
参考文献
Guerra, Krassimira P.; Afonso, Carlos A. M.
European Journal of Organic Chemistry, 2011 , # 12 p. 2372 - 2379
反应条件
hydrogenchloride; water
Hydrolysis;
参考文献
Jeong, Nakcheol; Hwang, Sung Hee
Angewandte Chemie - International Edition, 2000 , vol. 39, # 3 p. 636 - 638
