N(1),N(3)-二烯丙基尿嘧啶合成路线 （共 5 条）
反应条件
di-tert-butyl peroxide T=120 - 125°C; 6 h;
参考文献
Kovalev, G. B.; Rakhimov, A. I.; Ozerov, A. A.; Petrov, V. I.; Spasov, A. A.; et al.
Pharmaceutical Chemistry Journal, 1990 , vol. 24, # 6 p. 410 - 413
Khimiko-Farmatsevticheskii Zhurnal, 1990 , vol. 24, # 6 p. 25 - 27
反应条件
1: [131I]-Uracil With sodium hydride; dimethyl sulfoxide
T=20 - 60°C; 1 h; Inert atmosphere;
2: allyl bromide T=65°C; Inert atmosphereMicrowave irradiation;
参考文献
Sacarescu; Atudosie; Simionescu; Harabagiu
Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 5 p. 602 - 606
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; N,N-dimethyl-formamide
T=60°C;
参考文献
Amblard, Franck; Nolan, Steven P.; Gillaizeau, Isabelle; Agrofoglio, Luigi A.
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9177 - 9180
反应条件
palladium diacetate; triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt; 1,8-diazabicyclo[5.4.0]undec-7-ene in water; acetonitrile
T=60°C; 24 h;
参考文献
Goux, Catherine; Sigismondi, Silvana; Sinou, Denis; Perez, Montserrat; Moreno-Manas, Marcial; Pleixats, Roser; Villarroya, Merce
Tetrahedron, 1996 , vol. 52, # 28 p. 9521 - 9534
反应条件
in sodium hydroxide; acetone
参考文献
Tateoka; Kimura; Watanabe; Yamamoto; Ho
Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 12 p. 4928 - 4934
