3-(4-氟-苯基)-1-甲基-1H-吡唑-4-甲醛合成路线 (共 2 条)
反应条件
manganese(IV) oxide in tetrahydrofuran
T=20°C; 14 h;
参考文献
TAKEDA CHEMICAL INDUSTRIES, LTD.
Patent: WO2004/39365 A1, 2004 ;
Location in patent: Page/Page column 111-112 ;
WO 2004/039365 A1
反应条件
potassium carbonate in acetonitrile
T=20°C;
参考文献
Zheng, Weihong; Degterev, Alexei; Hsu, Emily; Yuan, Junying; Yuan, Chengye
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 4932 - 4935