反应条件
1: 1) thionyl chloride / 1a) room temp., 1 h, 1b) reflux, 30 min. 2: 32.5 g / 1.5 h / 150 °C / 15 Torr 3: 79 percent / sodium borohydride / ethanol / 2 h / Ambient temperature 4: 72 percent / p-toluenesulfonic acid, molecular sieves 4 A / toluene / Heating 5: 1) butyllithium, diisopropylamine / 1) hexane, THF,-70 deg C, 30 min, 2) THF, 15 min 6: 1) ozone, 2) pyridine / 1) CH2Cl2, -74 deg C, 2 h, 2) -74 deg C up to room temp. View Scheme
参考文献
Hamada; Hara; Kawai; Kohno; Shioiri
Tetrahedron, 1991 , vol. 47, # 40 p. 8635 - 8652
