3-氨基-2-甲基-苯甲腈合成路线 （共 10 条）
反应条件
sodium azide Multistep reaction;
参考文献
Dunkin; Shields
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 1997 , vol. 53, # 2 p. 141 - 150
反应条件
1: (i) aq. H2SO4, NaNO2, (ii) /BRN= 3587244/ 2: KOH View Scheme
参考文献
Wenkert,E. et al.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2534 - 2542
参考文献
Noelting
Chemische Berichte, 1904 , vol. 37, p. 1021
反应条件
(i) NaNO2, aq. H2SO4, (ii) KI; Multistep reaction;
参考文献
Gore,P.H. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 2940 - 2948
反应条件
1: (i) NaNO2, aq. H2SO4, (ii) KI 2: aq. NaOH View Scheme
参考文献
Gore,P.H. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 2940 - 2948
反应条件
(i) aq. H2SO4, NaNO2, (ii) /BRN= 3587244/; Multistep reaction;
参考文献
Wenkert,E. et al.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2534 - 2542
反应条件
ammonium chloride; zinc in tetrahydrofuran; methanol
T=0 - 20°C; 2 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; LIU, Chunjian; LIN, James; DELUCCA, George V.; BATT, Douglas G.; LIU, Qingjie
Patent: WO2011/159857 A1, 2011 ;
Location in patent: Page/Page column 78-79 ;
WO 2011/159857 A1
反应条件
palladium (II) trifluoroacetate; 2-(di-1-adamantylphosphanyl)-1-(2,6-diisopropylphenyl)-1H-imidazole; sodium carbonate in N,N-dimethyl acetamide
T=140°C; 16 h; Inert atmosphere;
参考文献
Schareina, Thomas; Jackstell, Ralf; Schulz, Thomas; Zapf, Alexander; Cotte, Alain; Gotta, Matthias; Beller, Matthias
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 4 p. 643 - 648
反应条件
1: 2.) CuCN
2: Zn / H2O; ethanol
View Scheme
参考文献
Dunkin; Shields
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 1997 , vol. 53, # 2 p. 141 - 150
反应条件
1: (i) NaNO2, aq. H2SO4, (ii) KI
2: aq. NaOH
View Scheme
参考文献
Gore,P.H. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 2940 - 2948
