1-(5-溴-吡啶-2-基)-吡咯烷-3-二甲胺合成路线 （共 3 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=250°C; 0.5 h; Microwave irradiation;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2007/141200 A1, 2007 ;
Location in patent: Page/Page column 31 ;
反应条件
N-ethyl-N,N-diisopropylamine in methanol; water
T=120°C; 15 h; Sealed vessel;
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/76387 A1, 2009 ;
Location in patent: Page/Page column 20 ;
WO 2009/076387 A1
反应条件
sodium carbonate in ethyl acetate; butan-1-ol
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: US2004/209865 A1, 2004 ;
US 20040209865 A1
