4-(2-硝基苯氧基)四氢-1(2H)-吡啶羧酸叔丁酯合成路线 （共 4 条）
反应条件
triphenylphosphine; diethylazodicarboxylate T=20°C; Mitsunobu reaction; 2 h;
参考文献
PIERRE FABRE MEDICAMENT; Dupont-Passelaigue, Elisabeth; Le Roy, Isabelle; Pignier, Christophe
Patent: US2013/172326 A1, 2013 ;
Location in patent: Paragraph 0135 ;
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=3750.38 Torr; 2 h;
参考文献
PIERRE FABRE MEDICAMENT; Dupont-Passelaigue, Elisabeth; Le Roy, Isabelle; Pignier, Christophe
Patent: US2013/172326 A1, 2013 ;
Location in patent: Paragraph 0136 ;
反应条件
hydrogenchloride in 1,4-dioxane T=20°C; 1 h;
参考文献
Forest Laboratories Holdings Limited
Patent: US2009/239810 A1, 2009 ;
Location in patent: Page/Page column 24 ;
US 20090239810 A1
反应条件
hydrogen; palladium on activated charcoal in methanol
T=20°C; P=3750.38 Torr; 2 h;
参考文献
PIERRE FABRE MEDICAMENT; DUPONT-PASSELAIGUE, Elisabeth; LE ROY, Isabelle; PIGNIER, Christophe
Patent: WO2012/69503 A1, 2012 ;
Location in patent: Page/Page column 25 ;
