1: 2-ethoxycarbonylacetyl chloride; Ethyl 2-[(3-methylbutyl)amino]-3-pyridinecarboxylate in dichloromethane T=20°C; 1 h; 2: With triethylamine in dichloromethane 3: 2-ethoxycarbonylacetyl chloride With hydrogenchloride; sodium ethanolate; sodium hydrogencarbonate more than 3 stages;
参考文献
FITCH, Duke M.; Colon, Mariela
Patent: US2007/213335 A1, 2007 ;
Location in patent: Page/Page column 7-8 ;
