2,4-二氯-3-甲基苯磺酰氯合成路线 （共 4 条）
反应条件
1.1: 84 percent / KF; Ph4PBr / tetrahydrothiophene 1,1-dioxide; toluene / 1.5 h / 210 °C 2.1: NaOH; H2O / 1 h 2.2: 79.1 percent / H2SO4; H2O / Heating View Scheme
参考文献
Suzuki, Hiroshi; Kageyama, Hiroyuki; Yoshida, Yasuo; Kimura, Yoshikazu
Journal of Fluorine Chemistry, 1991 , vol. 55, # 3 p. 335 - 337
反应条件
dibenzoyl peroxide in tetrachloroethane, 1,1,2,2-
参考文献
Fournier Industrie et Sante
Patent: US6080758 A1, 2000 ;
反应条件
chlorosulfonic acid
T=40°C; 2 h;
参考文献
ISTITUTO LUSO FARMACO D'ITALIA S.P.A.
Patent: WO2006/40004 A1, 2006 ;
Location in patent: Page/Page column 9 ;
WO 2006/040004 A1
反应条件
triethylamine in dichloromethane
T=20°C; 15 h;
参考文献
Barth, Martine; Bondoux, Michel; Luccarini, Jean-Michel; Peyrou, Vincent; Dodey, Pierre; Pruneau, Didier; Massardier, Christine; Paquet, Jean-Luc
Journal of Medicinal Chemistry, 2012 , vol. 55, # 6 p. 2574 - 2584
