(Z)-1-苯基-2-(溴甲基)环丙烷羧酸合成路线 （共 4 条）
反应条件
1: 90 percent / SOCl2 / 2 h / Heating 2: diethyl ether / Ambient temperature 3: dimethylformamide / 2.5 h / 110 °C 4: H2NNH2 / ethanol / Heating 5: 80 percent / pyridine / Ambient temperature View Scheme
参考文献
Bonnaud, Bernard; Cousse, Henri; Mouzin, Gilbert; Briley, Mike; Stenger, Antoine; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 318 - 325
反应条件
1: 90 percent / SOCl2 / 2 h / Heating 2: diethyl ether / Ambient temperature 3: dimethylformamide / 2.5 h / 110 °C View Scheme
参考文献
Bonnaud, Bernard; Cousse, Henri; Mouzin, Gilbert; Briley, Mike; Stenger, Antoine; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 318 - 325
反应条件
1: 90 percent / SOCl2 / 2 h / Heating 2: diethyl ether / Ambient temperature 3: dimethylformamide / 2.5 h / 110 °C 4: H2NNH2 / ethanol / Heating 5: Et3N / dioxane / 15 h / Ambient temperature 6: H2NNH2*H2O / ethanol / 2 h / Heating View Scheme
参考文献
Bonnaud, Bernard; Cousse, Henri; Mouzin, Gilbert; Briley, Mike; Stenger, Antoine; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 318 - 325
反应条件
1: 90 percent / SOCl2 / 2 h / Heating 2: diethyl ether / Ambient temperature 3: dimethylformamide / 2.5 h / 110 °C View Scheme
参考文献
Bonnaud, Bernard; Cousse, Henri; Mouzin, Gilbert; Briley, Mike; Stenger, Antoine; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 318 - 325
