Van Heerden, Pieter S.; Bezuidenhoudt, Barend C. B.; Ferreira, Daneel
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 8 p. 1141 - 1146
1: diethyl ether / 20 °C / |Inert atmosphere
2: hydrogenchloride / water; diethyl ether / 90 °C
View Scheme
参考文献
Baez-Santos, Yahira M.; Barraza, Scott J.; Wilson, Michael W.; Agius, Michael P.; Mielech, Anna M.; Davis, Nicole M.; Baker, Susan C.; Larsen, Scott D.; Mesecar, Andrew D.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2393 - 2412
1: cyclohexanecarboxylic acid With 1,1'-carbonyldiimidazole in dichloromethane
T=0°C; 1 h;
2: With O,N-dimethyl-hydroxylamine hydrochloride; triethylamine in dichloromethane
T=20°C;
3: chloro(phenylmethyl)-magnesium With water; ammonium chloride
more than 3 stages;
参考文献
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA
Patent: WO2006/8556 A1, 2006 ;
Location in patent: Page/Page column 22 ;
in tetrahydrofuran; diethyl ether; water; ethyl acetate
参考文献
Godfrey, Alexander Glenn; Kohlman, Daniel Timothy; O'Toole, John Cunningham; Xu, Yao-Chang; Zhang, Tony Yantao
Patent: US2004/44009 A1, 2004 ;
US 20040044009 A1
