2′-羟基-4′-甲基苯乙酮合成路线 （共 85 条）
参考文献
Goethals, G.; Nadio, L.; Uzan, R.
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy, 1981 , vol. 37, # 3 p. 199 - 204
反应条件
hydroxylamine hydrochloride; sodium hydroxide in ethanol; water
参考文献
Kociolek, Martin George; Casbohm, Jerry S.
Journal of Physical Organic Chemistry, 2013 , vol. 26, # 10 p. 863 - 867
反应条件
1: aqueous NaOH; aqueous H2O2 2: sodium acetate / 140 - 150 °C View Scheme
参考文献
Ono; Imoto
Bulletin of the Chemical Society of Japan, 1936 , vol. 11, p. 127,131
Nippon Kagaku Kaishi, 1936 , vol. 57, p. 112,118
反应条件
hydrogenchloride; zinc in ethanol 54 h; Heating;
参考文献
Thakar; Joshi
Journal of the Indian Chemical Society, 1982 , vol. 59, # 1 p. 77 - 79
反应条件
hydrogenchloride; sodium hydroxide; NaH in benzene
参考文献
Grimm, Erich L.; Ducharme, Yves; Frenette, Richard; Friesen, Richard; Gagnon, Marc; Juteau, Helene; Laliberte, Sebastien; MacKay, Bruce; Gareau, Yves
Patent: US2008/188521 A1, 2008 ;
Location in patent: Page/Page column 18 ;
反应条件
1: 2 h / 80 - 90 °C 2: 60 percent / NH2OH*HCl / ethanol / 0.5 h / Heating View Scheme
参考文献
Ghosh, Tarun; Saha, Satyajit; Bandyopadhyay, Chandrakanta
Synthesis, 2005 , # 11 art. no. T14704SS, p. 1845 - 1849
反应条件
pyridine T=20°C; 18 h;
参考文献
Alantos Pharmaceuticals, Inc.,
Patent: US2006/173183 A1, 2006 ;
Location in patent: Page/Page column 100 ;
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium; dimethyl sulfoxide in hexane
T=20°C;
2: 4-methyl-2-hydroxyacetophenone in hexane; dimethyl sulfoxide
Wittig reaction;
参考文献
Ferguson, Jamie; Zeng, Fanlong; Alper, Howard
Organic Letters, 2012 , vol. 14, # 21 p. 5602 - 5605,4
反应条件
1: 73 percent / 160 °C
View Scheme
参考文献
Desai, D. G.; Rane, R. K.; Mane, R. B.
Journal of the Indian Chemical Society, 1984 , vol. 61, # 5 p. 453 - 455
反应条件
1.1: sodium hydride / tetrahydrofuran / 72 h / 0 - 20 °C / |Inert atmosphere
1.2: |Inert atmosphere
2.1: palladium diacetate; 1,4-di(diphenylphosphino)-butane; p-benozquinone / acetonitrile / 20 h / 110 °C / 5171.62 Torr / |Autoclave
View Scheme
参考文献
Ferguson, Jamie; Zeng, Fanlong; Alper, Howard
Organic Letters, 2012 , vol. 14, # 21 p. 5602 - 5605,4
