2’-氟-5-甲基阿拉伯糖基尿嘧啶合成路线 （共 19 条）
反应条件
ammonium hydroxide in methanol T=20°C; 24 h;
参考文献
Wang, Qiang; Li, Yanfeng; Song, Chuanjun; Qian, Keduo; Chen, Chin-Ho; Lee, Kuo-Hsiung; Chang, Junbiao
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 14 p. 4053 - 4056
反应条件
in methanolic ammonia
参考文献
US4211773 A1, ;
US4594339 A1, ;
反应条件
1.1: 90 percent / HBr / CH2Cl2 / 24 h / 20 °C 2.1: CCl4 / 72 h / 77 °C 2.2: NH4OH / methanol / 24 h / 20 °C View Scheme
参考文献
Nucleosides, nucleotides and nucleic acids, , vol. 22, # 5-8 p. 1343 - 1346
反应条件
1: in tetrachloromethane T=77°C; 72 h; 2: With ammonium hydroxide in methanol T=20°C; 24 h;
参考文献
Nucleosides, nucleotides and nucleic acids, , vol. 22, # 5-8 p. 1343 - 1346
反应条件
1: (NH4)2SO4 / Heating 2: CH2Cl2 / 168 h / Ambient temperature 3: NH3 / methanol / Ambient temperature 4: 1.) 75percent AcOH, 2.) NH3 / 1.) reflux, 48 h, 2.) MeOH, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 152 - 156
反应条件
1: CH2Cl2 / 168 h / Ambient temperature 2: NH3 / methanol / Ambient temperature 3: 1.) 75percent AcOH, 2.) NH3 / 1.) reflux, 48 h, 2.) MeOH, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 152 - 156
反应条件
1: HBr gas / CH2Cl2 / 4 °C 2: CH2Cl2 / 168 h / Ambient temperature 3: NH3 / methanol / Ambient temperature 4: 1.) 75percent AcOH, 2.) NH3 / 1.) reflux, 48 h, 2.) MeOH, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 152 - 156
反应条件
1: NH3 / methanol / Ambient temperature 2: 1.) 75percent AcOH, 2.) NH3 / 1.) reflux, 48 h, 2.) MeOH, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 152 - 156
反应条件
sodium hydroxide in methanol 16 h; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 50, # 19 p. 3644 - 3647
反应条件
1: ammonium sulfate / acetonitrile / 3 h / Heating 2: CCl4 / 60 h / Heating 3: liquid ammonia; methanol / 65 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, p. 85 - 88
