(S)-2-氨基-3-(3,4-二甲氧基苯基)-2-甲基丙酸盐酸盐合成路线 （共 6 条）
反应条件
hydrogenchloride in water 1) 3h, 90 deg C, 2) 0 deg C, 16h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
O'Reilly; Derwin; Lin
Synthesis, 1990 , # 7 p. 550 - 556
反应条件
hydrogenchloride; formaldehyd in P2O5; water
参考文献
Occidental Chemical Corporation
Patent: US4912221 A1, 1990 ;
反应条件
hydrogenchloride in water
20 h; Heating;
参考文献
Occidental Chemical Corporation
Patent: US4912221 A1, 1990 ;
反应条件
1: 84 percent / Na2CO3
2: H2 / <Rh(R-PROPHOS)(NBD)>PF6 / tetrahydrofuran / 17 h
3: 94.8 percent / conc. HCl / H2O / 20 h / Heating
View Scheme
参考文献
O'Reilly; Derwin; Lin
Synthesis, 1990 , # 7 p. 550 - 556
反应条件
1: H2 / <Rh(R-PROPHOS)(NBD)>PF6 / tetrahydrofuran / 17 h
2: 94.8 percent / conc. HCl / H2O / 20 h / Heating
View Scheme
参考文献
O'Reilly; Derwin; Lin
Synthesis, 1990 , # 7 p. 550 - 556
反应条件
1: 68 percent / acetic anhydride / Heating
2: 84 percent / Na2CO3
3: H2 / <Rh(R-PROPHOS)(NBD)>PF6 / tetrahydrofuran / 17 h
4: 94.8 percent / conc. HCl / H2O / 20 h / Heating
View Scheme
参考文献
O'Reilly; Derwin; Lin
Synthesis, 1990 , # 7 p. 550 - 556
