2-甲基-2-丙基(3R,4S)-3-{[(4R)-4-苄基-2-氧代-1,3-恶唑烷-3-基]羰基}-4-甲基己酸酯合成路线 （共 5 条）
反应条件
1: 80 percent / (COCl)2 / CH2Cl2 / 0 - 20 °C
2: 79 percent / n-BuLi / -78 °C
3: NaHMDS / -78 °C
View Scheme
参考文献
Armstrong, Alan; Scutt, James N
Chemical communications (Cambridge, England), 2004 , # 5 p. 510 - 511
反应条件
1: 74 percent / H2NOSO3H; aq. KOH / 0 - 20 °C
2: 80 percent / (COCl)2 / CH2Cl2 / 0 - 20 °C
3: 79 percent / n-BuLi / -78 °C
4: NaHMDS / -78 °C
View Scheme
参考文献
Armstrong, Alan; Scutt, James N
Chemical communications (Cambridge, England), 2004 , # 5 p. 510 - 511
反应条件
sodium hexamethyldisilazane
T=-78°C;
参考文献
Armstrong, Alan; Scutt, James N
Chemical communications (Cambridge, England), 2004 , # 5 p. 510 - 511
反应条件
1: 79 percent / n-BuLi / -78 °C
2: NaHMDS / -78 °C
View Scheme
参考文献
Armstrong, Alan; Scutt, James N
Chemical communications (Cambridge, England), 2004 , # 5 p. 510 - 511
反应条件
lithium hydroxide; dihydrogen peroxide
T=0 - 20°C;
参考文献
Armstrong, Alan; Scutt, James N
Chemical communications (Cambridge, England), 2004 , # 5 p. 510 - 511
