2-吗啉-4-基丙烷-1-醇合成路线 (共 4 条)
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0°C; 1 h;
参考文献
AMGEN INC.
Patent: WO2006/12374 A1, 2006 ;
Location in patent: Page/Page column 131 ;
WO 2006/012374 A1
反应条件
potassium carbonate
T=150°C;
参考文献
Attenburrow et al.
Journal of the Chemical Society, 1949 , p. 510,515
Full Text Show Details
Halverstadt et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 3618,3620
参考文献
Amgen Inc.
Patent: US6878714 B2, 2005 ;
US 6878714 B2
反应条件
in methanol
T=45°C; 3 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Moore,G.G.; Hansen,J.C.
Journal of Fluorine Chemistry, 1986 , vol. 32, p. 41