N,N'-二异丙基碳二亚胺合成路线 （共 71 条）
反应条件
(i), (ii) decalin; Multistep reaction;
参考文献
Tsuboi,S. et al.
Tetrahedron Letters, 1976 , p. 1145 - 1148
反应条件
sodium hydroxide in tetrahydrofuran
T=20°C; 2 h;
参考文献
Lee, Jean; Chubb, Anthony J.; Moman, Edelmiro; McLoughlin, Brian M.; Sharkey, Caroline T.; Kelly, John G.; Nolan, Kevin B.; Devocelle, Marc; Fitzgerald, Desmond J.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3678 - 3685
反应条件
1: N-(fluoren-9-ylmethoxycarbonyl)-L-Lys(Nε-Boc); diisopropyl-carbodiimide in dichloromethane
T=20°C; 0.25 h;
2: C8H10NPol in dichloromethane
T=20°C;
参考文献
Migenix Inc.
Patent: US2007/21434 A1, 2007 ;
Location in patent: Page/Page column 16-17; 74 ;
反应条件
in tetrahydrofuran
T=75 - 79°C; 1.41667 h; Product distribution / selectivity;
参考文献
Wyeth Holdings Corporation
Patent: US2005/43537 A1, 2005 ;
Location in patent: Page/Page column 5-6 ;
反应条件
in dichloromethane
T=20°C; 14 h; Title compound not separated from byproducts.;
参考文献
Del Pozo, Carlos; Keller, Adam I.; Nagashima, Tadamichi; Curran, Dennis P.
Organic Letters, 2007 , vol. 9, # 21 p. 4167 - 4170
反应条件
oxygen in toluene
7 h; RefluxAir atmosphere;
参考文献
Ispikoudi, Maria; Amvrazis, Michalis; Kontogiorgis, Christos; Koumbis, Alexandros E.; Litinas, Konstantinos E.; Hadjipavlou-Litina, Dimitra; Fylaktakidou, Konstantina C.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5635 - 5645
反应条件
oxygen in toluene
6 h; RefluxAir atmosphere;
参考文献
Ispikoudi, Maria; Amvrazis, Michalis; Kontogiorgis, Christos; Koumbis, Alexandros E.; Litinas, Konstantinos E.; Hadjipavlou-Litina, Dimitra; Fylaktakidou, Konstantina C.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5635 - 5645
反应条件
oxygen in toluene
6 h; RefluxAir atmosphere;
参考文献
Ispikoudi, Maria; Amvrazis, Michalis; Kontogiorgis, Christos; Koumbis, Alexandros E.; Litinas, Konstantinos E.; Hadjipavlou-Litina, Dimitra; Fylaktakidou, Konstantina C.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5635 - 5645
反应条件
oxygen in toluene
6 h; RefluxAir atmosphere;
参考文献
Ispikoudi, Maria; Amvrazis, Michalis; Kontogiorgis, Christos; Koumbis, Alexandros E.; Litinas, Konstantinos E.; Hadjipavlou-Litina, Dimitra; Fylaktakidou, Konstantina C.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5635 - 5645
反应条件
oxygen in toluene
6 h; RefluxAir atmosphere;
参考文献
Ispikoudi, Maria; Amvrazis, Michalis; Kontogiorgis, Christos; Koumbis, Alexandros E.; Litinas, Konstantinos E.; Hadjipavlou-Litina, Dimitra; Fylaktakidou, Konstantina C.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5635 - 5645
