2,6-二溴甲苯合成路线

NOVARTIS AG; ASTEX THERAPEUTICS LIMITED; HOWARD, Steven; MORTENSON, Paul Neil; HISCOCK, Steven Douglas; WOOLFORD, Alison Jo-Anne; WOODHEAD, Andrew James; CHESSARI, Gianni; O'REILLY, Marc; CONGREVE, Miles Stuart; DAGOSTIN, Claudio; CHO, Young Shin; YANG, Fan; CHEN, Christine Hiu-Tung; BRAIN, Christopher Thomas; LAGU, Bharat; WANG, Yaping; KIM, Sunkyu; GRIALDES, John; LUZZIO, Michael Joseph; PEREZ, Lawrence Blas
Patent: WO2010/125402 A1, 2010 ;
Location in patent: Page/Page column 121-122 ;
WO 2010/125402 A1

69321-60-42,6-二溴甲苯

108-36-11,3-二溴苯

参考文献

Lock
Chemische Berichte, 1935 , vol. 68, p. 1505,1508

69321-60-42,6-二溴甲苯

1147858-83-02,6-二溴乙酸苄酯

参考文献

GILEAD CONNECTICUT, INC.; GENENTECH, INC.; CURRIE, Kevin S.; WANG, Xiaojing; YOUNG, Wendy B.
Patent: WO2012/31004 A1, 2012 ;
WO 2012/031004 A1

69321-60-42,6-二溴甲苯

21900-48-13-溴-2-甲基苯(甲)酰氯

参考文献

GLAXO GROUP LIMITED
Patent: WO2009/100169 A1, 2009 ;
WO 2009/100169 A1

7677-24-9三甲基氰硅烷+

69321-60-42,6-二溴甲苯

67197-53-92,6-二溴-苯乙腈

参考文献

Hitce, Julien; Baudoin, Olivier
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 11-12 p. 2054 - 2060

69321-60-42,6-二溴甲苯+

68-12-2N,N-二甲基甲酰胺

83647-40-93-溴-2-甲基苯甲醛

参考文献

GLAXO GROUP LIMITED; DENG, Guanghui; LIN, Xichen; REN, Feng; ZHAO, Baowei
Patent: WO2011/134280 A1, 2011 ;
Location in patent: Page/Page column 80 ;
WO 2011/134280 A1