2,5-二甲基-2-(3-甲基-2-丁烯-1-基)-4-己烯腈合成路线 （共 3 条）
反应条件
n-butyllithium; ammonium chloride; diisopropylamine in tetrahydrofuran
参考文献
Smets, Johan; Denutte, Hugo Robert Germain; Pintens, An; Van Aken, Koen; Vrielynck, Freek Annie Camiel
Patent: US2011/308556 A1, 2011 ;
反应条件
lithium diisopropyl amide
1) ether, hexane, -65 deg C, 30 min, 2) -65 deg C, 1.5 h, then rt, 1 h; Multistep reaction;
参考文献
Dworniczak, Miroslaw; Leffek, Kenneth T.
Canadian Journal of Chemistry, 1990 , vol. 68, # 10 p. 1657 - 1661
→
69340-58-51,2,3,4,4a,5,6,7-八氢-2,2,4a,7,7-五甲基萘啶
反应条件
1: NaNH2 / benzene; toluene / 8 h / Heating
2: 1) gaseous HCl / 1) CH2Cl2, 0 deg C, 2) 200 deg C
View Scheme
参考文献
Dworniczak, Miroslaw; Leffek, Kenneth T.
Canadian Journal of Chemistry, 1990 , vol. 68, # 10 p. 1657 - 1661
